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Global Projects

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Sustainable Habit Program

Cape Coast Ghana

Earth Bag Seed Bank Project in partnership with Adamah Ver Zerah

Low Cost Building Research Trip to Ghana – June 2021

Members of the Sustainable Habit Program will be on site for 1 month as the last stage before the “Build” faze goes into effect. This program needs more support in the form of members interested in going to Ghana Africa June 2021. We will be seeking to build showers in “Rural” areas of the country.

Ghana Home Project Example
Cameroon Medical Herb Progress

Medicinal herb seed & plant gathering

Goals: To attain herbs & seeds to grow herbs to enrich the Earthbag Seed Bank Project in collaboration with ADAMAH VER ZERAH.

Location: Yaounde Cameroon & surrounding areas.

Medical Herb List

Family - Species - Traditional treatment - Plant part used Bioactive (or potentially active) compounds - Screened activity

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Acanthaceae

Thomandersia hensii De Wild and Th. Dur (LB Th 0301)

Malaria, diarrhea, colitis, furuncles, abscesses, syphilis, ulcers, urogenital disorders, intestinal parasites, debility, tiredness, edema, rheumatism, eye inflammations (Letouzey, 1985; Ngadjui et al, 1994)

 

Bark, leaves, pulp, sap, roots

Not identified

IC50 < 30 μg/ml reported for hexane extract from the stem bark on P. falciparum W2 (Indochina I/CDC) chloroquine-resistant strain (Bickii et al., 2007b)

Annonaceae

Uvariopsis congolana (De Wild) Fries (37016/HNC)

Malaria (Boyom et al., 2009)

 

Bark, leaves

Not identified, but plants of this family were reported to contain acetogeninsc IC50 < 5 μg/ml reported for the crude extract from the leaves and bark on P. falciparum strain W2 (Boyom et al., 2009)

Polyalthia oliveri Engl. (19416 SRF/Cam)

Malaria (Boyom et al., 2009)

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Apocynaceae

Picralima nitida Stapf (LB Pn 0301)

Malaria, diarrhoea, intestinal worms, gonorrhoea, inflammation (Letouzey, 1985; Ezeamuzie et al., 1994; Fakeye et al., 2000)

Bark, roots, seeds; fruits

Not identified

IC50 < 30 μg/ml reported for the methanol and dichloromethane–methanol 1:1 extracts from the seeds and bark on P. falciparum W2 (Indochina I/CDC) chloroquine-resistant strain (Bickii et al., 2007b)

Euphorbiaceae

Croton zambesicus Muell. Arg. (8204/SRFCam)

Malaria (Boyom et al., 2009)

 

Bark

Not identified, IC50 < 10 μg/ml reported for the crude extract from the bark on P. falciparum strain W2 (Boyom et al., 2009)

Neoboutonia glabrescens Müll. Arg. Prain (7433/SRFCam)

Malaria (Boyom et al., 2009)

Bark, leaves

Not identified, IC50 < 10 μg/ml reported for the crude extract from the leaves and bark on P. falciparum strain W2 (Boyom et al., 2009)

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Guttiferae

Symphonia globulifera Linn f. (50788/HNC)

Stomach and skin aches, laxative for pregnant women, general tonic, Malaria (Aubreville, 1950; Irvine, 1961; Ngouela et al., 2006).

Bark

Gaboxanthone (38); symphonin (39); globuliferin (40); guttiferone A (50) (Ngouela et al., 2006).

IC50 <20 μM on P. falciparum reported for compounds 38–40 and 50 (Ngouela et al., 2006).

Lauraceae

Beilschmiedia zenkeri Engl.

Not reported

Bark

5-Hydroxy-7,8-dimethoxyflavone; pipyahyine; betulinic acid (Lenta et al., 2009)

IC50 <5 μM on chloroquine-resistant P. falciparum reported for pipyahyine (Lenta et al., 2009)

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Meliaceae

Entandrophragma angolense Welwitsch C.D.C. (29933/HNC)

Malaria (Bickii et al., 2007a)

Bark and Seeds

Methylangolensate (1); 6-methylhydroxyangolensate (2); gedunin (3); catechin; 7-deacetylkhivorin (4); 1-deacetylkhivorin (5); swietenolide (6); 6-acetylswietenolide (7) (Bickii et al., 2000)

IC50 < 20 μg/ml on P. falciparum W2 strain reported for bark and seeds extracts; compounds 1–7. Compound 3 exhibited an additive effect when combined with chloroquine (Bickii et al., 2000)

Turreanthus Africanus

Malaria and other fevers (Zhou et al., 1997)

Bark, seeds, leaves

16-oxolabda-8 (17), 12(E)-dien-15-oic acid; methyl-14, 15-epoxylabda-8 (17), 12(E)-diene-16-oate; turreanin A (Ngemenya et al., 2006)

None of the active compounds exhibited IC50 < 20 μg/ml on P. falciparum F 32, chloroquine sensitive strain (Ngemenya et al., 2006)

Agapanthus.webp
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Moraceae

Artocarpus communis J.R. & G. Forst (43982 HNC)

Malaria (Boyom et al., 2009)

Bark, leaves

Not identified, IC50 < 10 μg/ml reported for the crude extract from the leaves and bark on P. falciparum strain W2 (Boyom et al., 2009)

Dorstenia convexa De Wild (53450 HNC)

Malaria (Boyom et al., 2009)

Twigs

Not identified, IC50 < 10 μg/ml reported with the crude extract from the twigs on P. falciparum strain W2 (Boyom et al., 2009)

Zingiberaceae

Aframomum zambesiacum (Baker) K. Schum (37737HNY)

Malaria (Kenmogne et al., 2006)

Seeds

Aulacocarpin A (11); aulacocarpin B; 3-deoxyaulacocarpin A (12); methyl-14n,15-epoxy-3b-hydroxy-8(17),12-elabdadien-16-oate; galanolactone; zambesiacolactone A (13); zambesiacolactone B (14); aframodial (Kenmogne et al., 2006)

IC50 < 20 μM on P. falciparum reported for compounds 11–14 (Kenmogne et al., 2006)

Reneilmia cincinnata (K. Schum.) Bak.

Malaria (Tchuendem et al., 1999)

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To support the youth population in a way that advances their ability to affect the communities they are in. Not be a victim to the situations around them, but to grow together and share ideas, then put them into action.
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Address: Northern California

WhatsApp: +17073729573

Email: ykborganization@gmail.com

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